(+)-JQ-1 AS A BET INHIBITOR SECRETS

Indeed, TERT phosphorylation has been shown to be demanded for telomerase activation. b Result of BETi on telomere regulation. BETi contend with acetylated histones for that binding on the BRD4 bromodomains releasing BRD4 from brief telomere, destabilizing telomere protection advanced Firm and reducing Telomerase activity. The progressive shortenin